Which group is always a vulnerable population specifically protected in IRB review?

Children under age 18 are recognized as a vulnerable population that requires specific protections in Institutional Review Board (IRB) reviews. This protection stems from the recognition that minors may lack the capacity to provide informed consent and are particularly susceptible to coercion. Their developmental stage makes them more reliant on adults for guidance, which calls for stricter ethical standards when involving them in research.

The regulations governing IRB reviews emphasize the need for additional safeguards for children, ensuring their rights and welfare are adequately protected throughout the research process. This includes obtaining assent from the child whenever possible, along with informed consent from their legal guardians. By establishing these protocols, researchers can work towards minimizing risks and promoting the well-being of younger participants in studies.

In comparison, while other groups like prisoners, elderly individuals, and internally displaced persons also have protective measures, the specific and universal designation for minors during IRB reviews highlights their unique status and the ethical imperative to prioritize their safety and rights in research contexts.